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COLUMBIA LABORATORIES ADDED TO NASDAQ BIOTECHNOLOGY INDEX LIVINGSTON, NJ— May 15, 2006—Columbia Laboratories, Inc. (NASDAQ: CBRX) has been added to the NASDAQ Biotechnology Index® (NASDAQ: NBI) effective at the market open on Monday, May 22, 2006. Launched in 1993, the NASDAQ Biotechnology Index includes securities of NASDAQ listed companies classified as either biotechnology or pharmaceutical according to the Industry Classification Benchmark (ICB), and which also meet other criteria. The NASDAQ Biotechnology Index is ranked on a semi-annual basis in May and November. All securities in the NASDAQ Biotechnology Index are listed on the NASDAQ National Market and meet specific criteria, including market value, average daily share volume and seasoning as a public company. For more information about the NASDAQ Biotechnology Index, including eligibility criteria, visit http://www.nasdaq.com. About Columbia Laboratories Columbia Laboratories, Inc. is a U.S.-based international pharmaceutical company dedicated to the development and commercialization of women's health care and endocrinology products. Columbia markets Prochieve® 8% (progesterone gel) for progesterone supplementation as part of an Assisted Reproductive Technology treatment for infertile women with progesterone deficiency and Prochieve® 4% (progesterone gel) for the treatment of secondary amenorrhea. The Company also markets Striant® (testosterone buccal system) for the treatment of hypogonadism in men. Columbia's products and product candidates utilize the Company's bioadhesive drug delivery technology, which is able to deliver a broad range of compounds, including peptides, across many of the body’s mucosal surfaces to address numerous therapeutic areas. The Company is investigating the potential utility of Prochieve® 8% (progesterone gel) in the prevention of preterm birth and developing a vaginally-administered lidocaine product to treat dysmenorrhea and pelvic pain. For more information, please visit www.columbialabs.com. Prochieve® and Striant® are registered trademarks of Columbia Laboratories, Inc. ### |